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Science Behind Snooze Boost
Pyridoxine (B6) for Dreaming
The impact of pyridoxine (Vitamin B-6) on dreaming was explored in a placebo, double-blind study involving 12 college students. Participants ingested 100 mg B-6, 250 mg B-6, or a placebo before bedtime for five consecutive days. Morning self-reports revealed a significant difference in dream-salience scores between the 250-mg condition and placebo during the initial three days of each treatment. The data suggests that Vitamin B-6 might enhance dream vividness by increasing cortical arousal during REM sleep. Replication studies and sleep laboratory validation are recommended for conclusive results.
https://pubmed.ncbi.nlm.nih.gov/11883552/
Melatonin Supplementation on Sleep Quality
The study aimed to systematically review the impact of melatonin on sleep quality, focusing on adults with various diseases. A total of 23 randomized clinical trials (RCTs) were analyzed, using the Pittsburgh Sleep Quality Index (PSQI) as the assessment tool. Results, presented as mean differences (MD) with 95% confidence intervals, indicated a significant positive effect of melatonin on sleep quality (WMD: -1.24; 95% CI -1.77, -0.71, p = 0.000). Subgroup analysis revealed variations in the impact based on health status, with significant effects observed in subjects with respiratory diseases, metabolic disorders, and primary sleep disorders. Overall, exogenous melatonin demonstrated positive effects on sleep quality in adults across various health conditions.
https://pubmed.ncbi.nlm.nih.gov/33417003/
Sleep Parameters in Passiflora
This double-blind, randomized, placebo-controlled study investigated Passionflower's impact on sleep parameters in 110 adults with insomnia disorder. After a two-week intervention, Passionflower significantly increased total sleep time (TST) compared to placebo. Sleep efficiency and wake after sleep onset (WASO) also improved in the Passionflower group. The study suggests positive effects on objective sleep parameters, calling for further research to confirm clinical efficacy in treating insomnia.
https://pubmed.ncbi.nlm.nih.gov/31714321/